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Symbol Name ID |
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1 MGI:1346882 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased T cell proliferation |
abnormal dendritic cell physiology |
abnormal dendritic cell antigen presentation |
abnormal humoral immune response |
abnormal cytokine secretion |
increased interleukin-1 beta secretion |
increased interleukin-12 secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to experimental autoimmune encephalomyelitis |
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| Availability | Mouse Genotype | |||||||||||
| Map4k1m1Anu/Map4k1m1Anu | * | |||||||||||
| Map4k1tm1Ssaw/Map4k1tm1Ssaw | ||||||||||||
| Map4k1tm1Tht/Map4k1tm1Tht | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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